Review Article
Mitochondrial Heterogeneity: Evaluating Mitochondrial Subpopulation Dynamics in Stem Cells
Figure 1
Mitochondrial heterogeneity between tissue types and within cells. (a)–(e) Transmission electron micrographs depicting mitochondrial features in mouse liver ((a), enlarged in (b)), mouse heart ((c), enlarged in (d)), and a primary-stage human oocyte (e). (f) A fluorescent micrograph depicting JC-1-labeled KGN cells demonstrates heterogeneity in mitochondrial membrane potential between cells and between individual subcellular mitochondrial populations. JC-1 monomers (green) indicate low Δψm and JC-1 aggregates (red) indicate high Δψm. Scale bars as marked.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |