WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells

Figure 5

JNK inhibition effect on the expression of WDR62 and hPSC specification to neural and glial progenitors. Q-PCR data shows significant expression increase of PAX6 (), EAAT1 (), and WDR62 () and decreased expression of CASP3 () in hPSC-derived neural progenitors treated with JNK inhibitor versus no treatment at day 14 neural induction ( independent experiments). Two-tailed t-test was used to assess significance. ; .