Stem Cells International / 2017 / Article / Fig 3

Research Article

Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

Figure 3

Methylation status and allele-specific expression of androgen receptor (AR) gene in the fibroblasts, skeletal muscle, and blood sample of a manifesting carrier of DMD (609) and derived iPS cells. Left panel: % is calculated based on the assumption that one of two alleles is methylated, and signal intensities from allele 1 + allele 2 are shown as 100%. However, not all iPS clones have XCI. Right panel: representative images of direct sequencing of the AR gene.

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