Avoidance of Total Knee Arthroplasty in Early Osteoarthritis of the Knee with Intra-Articular Implantation of Autologous Activated Peripheral Blood Stem Cells versus Hyaluronic Acid: A Randomized Controlled Trial with Differential Effects of Growth Factor Addition
Table 6
WOMAC score
Gr 1 ()
Gr 2 ()
Gr 3 ()
Time (months)
0
1
6
12
0
1
6
12
0
1
6
12
Total
218.5
131.1
68.7bb,cc,dd
52a,b
212.2
154.3
114.2cc,ee
75c,d
215.3
170.2
134.6dd,ee
126.8a,c,e,aa,bb
Pain
95.5
60
30.5ff,gg
28f,g
93.5
69
50ff
30g,h
96
83
64gg
57k,f,h,j
Stiffness
51
27.5
15.5hh
9l,m,n
49.5
32.5
21.5ii
20o,l
50
32.5
26.5hh,ii
31.5q,r,l
Function
69.3
43.6
22.7jj,kk
15s,t
69.3
52.8
42.7jj
25x,y
69.3
54.7
45.1kk
38.8z,s,x,za
Total: a = Gr 1 versus Gr 3, ; b = intra Gr 1 month 0 versus 12, ; c = Gr 2 versus Gr 3, ; d = intra Gr 2 month 0 versus 12, ; e = intra Gr 3 month 0 versus 12, ; aa = pooled Gr 1 & 2 versus Gr 3, ; bb = Gr1 month 6 versus Gr3 month 12, ; cc = Gr 1 month 6 versus Gr 2 month 6, ; dd = Gr 1 month 6 versus Gr 3 month 6, ; ee = Gr 2 month 6 versus Gr 3 month 6, . Pain: f = Gr 1 versus Gr 3, ; g = intra Gr 1 month 0 versus 12, ; h = Gr 2 versus Gr 3, ; i = intra Gr 2 month 0 versus 12, ; j = pooled Gr 1 & 2 versus Gr 3, ; k = intra Gr 3 month 0 versus 12, ; ff = Gr 1 pain month 6 versus Gr 2 month 6, ; gg = Gr 1 pain month 6 versus Gr 3 month 6, . Stiffness: l = Gr 1 versus Gr 2, ; m = Gr 1 versus Gr 3, ; n = intra Gr 1 month 0 versus 12, ; o = intra Gr 2 month 0 versus 12, ; q = pooled Gr 1 & 2 versus Gr 3, ; r = intra Gr 3 month 0 versus 12 ; Gr 2 versus Gr 3, ; hh = Gr 1 stiffness month 6 versus Gr 3 month 6, ; ii = Gr 2 stiffness month 6 versus Gr 3 month 6, . Function: s = Gr 1 versus Gr 3, ; t = intra Gr 1 month 0 versus 12, ; x = Gr 2 versus Gr 3, ; y = intra Gr 2 month 0 versus 12, ; z = pooled Gr 1 & 2 versus Gr 3, ; za = intra Gr 3 month 0 versus 12, ; jj = Gr 1 function month 6 versus Gr 2 month 6, ; kk = Gr 1 function month 6 versus Gr 3 month 6, .
