Figure 1: Particle characterization. (a) Representative observation of Si-HPMC and alginate particles obtained by oil dispersion and dripping method, respectively, and observed under light microscope. (b) Dispersity and size distribution of Si-HPMC and alginate particles investigated by laser diffraction technique. (c) Reproducibility and effect of dispersion parameters (time, temperature, and stirring speed) on Si-HPMC particle size. The operating conditions selected to generate Si-HPMC particles for the size distribution investigation (Figure 1(b)) and for the following experiments. . Scale bars = 70 μm and 2 mm for Si-HPMC and alginate particles, respectively.