Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate Balance between Matrix Metalloproteinases and Their Inhibitors in the Osteoarthritic Cartilage In Vitro

Figure 6

Distribution of the gene expression ratios in cartilage explants (CE) + adipose tissue-derived stem cells (ASC) versus CE in the following: (a) incomplete chondrocyte medium (IM) (), (b) in IM + human platelet growth factor-enriched plasma (PP) (), (c) in IM + PP+ IL-1β—interleukin-1β (). The box length represents the interquartile range with median. ▾—extreme cases with values more than 3 box lengths from the upper or lower edge of the box. ○—outliers with values between 1.5 and 3 box lengths from the upper or lower edge of the box. ; ; .

(a)

(b)

(c)