Comparison of the MicroRNA Expression Profiles of Male and Female Avian Primordial Germ Cell Lines

Figure 11

Analysis of the gga-miR-302 cluster member’s expression in chicken PGCs. Microarray analysis was performed on 4 PGC lines (2 female (FS111 and 5ZP) and 2 male (FS101 and 4ZP)). (a) Expression of the members of the gga-miR-302 cluster was compared. A heat map was generated using GenEx software (complete linkage and Spearman correlation analysis were performed). (b) A high ratio of gga-miR-302b-3p expression was observed compared to gga-miR-302b-5p in the low-proliferating 5ZP PGC line. Two strands of gga-miR-302b show concordant dysregulation.

(a)

(b)