Table of Contents Author Guidelines Submit a Manuscript
Stem Cells International
Volume 2018, Article ID 2405698, 12 pages
https://doi.org/10.1155/2018/2405698
Research Article

B7-H1 Expression Is Required for Human Endometrial Regenerative Cells in the Prevention of Transplant Vasculopathy in Mice

1Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China
2Tianjin General Surgery Institute, Tianjin, China
3Department of Vascular Surgery, Tianjin Fourth Central Hospital, Tianjin, China
4Faculty of Medicine, University of Toronto, Toronto, ON, Canada
5Department of Endocrinology, Tianjin Medical University General Hospital, Tianjin, China

Correspondence should be addressed to Hao Wang; moc.liamtoh@272acgnawh

Received 11 September 2017; Revised 2 January 2018; Accepted 17 January 2018; Published 14 March 2018

Academic Editor: Jun Liu

Copyright © 2018 Kui Ye et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. B. Colvin and R. N. Smith, “Antibody-mediated organ-allograft rejection,” Nature Reviews Immunology, vol. 5, no. 10, pp. 807–817, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. S. A. Lodhi, K. E. Lamb, and H. U. Meier-Kriesche, “Solid organ allograft survival improvement in the United States: the long-term does not mirror the dramatic short-term success,” American Journal of Transplantation, vol. 11, no. 6, pp. 1226–1235, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Chih, A. Y. Chong, L. M. Mielniczuk, D. L. Bhatt, and R. S. B. Beanlands, “Allograft vasculopathy: the Achilles’ heel of heart transplantation,” Journal of the American College of Cardiology, vol. 68, no. 1, pp. 80–91, 2016. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Söderlund and G. Rådegran, “Immunosuppressive therapies after heart transplantation — the balance between under- and over-immunosuppression,” Transplantation Reviews, vol. 29, no. 3, pp. 181–189, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. Lv, X. Xu, B. Zhang et al., “Endometrial regenerative cells as a novel cell therapy attenuate experimental colitis in mice,” Journal of Translational Medicine, vol. 12, no. 1, p. 344, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Lu, G. Shi, X. Xu et al., “Human endometrial regenerative cells alleviate carbon tetrachloride-induced acute liver injury in mice,” Journal of Translational Medicine, vol. 14, no. 1, p. 300, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Sun, J. Liu, W. Li et al., “Human endometrial regenerative cells attenuate renal ischemia reperfusion injury in mice,” Journal of Translational Medicine, vol. 14, no. 1, p. 28, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. X. Xu, X. Li, X. Gu et al., “Prolongation of cardiac allograft survival by endometrial regenerative cells: focusing on B-cell responses,” Stem Cells Translational Medicine, vol. 6, no. 3, pp. 778–787, 2017. View at Publisher · View at Google Scholar · View at Scopus
  9. X. Meng, T. E. Ichim, J. Zhong et al., “Endometrial regenerative cells: a novel stem cell population,” Journal of Translational Medicine, vol. 5, no. 1, p. 57, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Dong, G. Zhu, K. Tamada, and L. Chen, “B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion,” Nature Medicine, vol. 5, no. 12, pp. 1365–1369, 1999. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Wang, F. Qi, X. Dai et al., “Requirement of B7-H1 in mesenchymal stem cells for immune tolerance to cardiac allografts in combination therapy with rapamycin,” Transplant Immunology, vol. 31, no. 2, pp. 65–74, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Labat, D. Calise, J. C. Thiers et al., “Simultaneous orthotopic transplantation of carotid and aorta in the rat by the sleeve technique,” Laboratory Animals, vol. 36, no. 4, pp. 426–431, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. M. P. Murphy, H. Wang, A. N. Patel et al., “Allogeneic endometrial regenerative cells: an “off the shelf solution” for critical limb ischemia?” Journal of Translational Medicine, vol. 6, no. 1, p. 45, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. C. H. Cui, T. Uyama, K. Miyado et al., “Menstrual blood-derived cells confer human dystrophin expression in the murine model of Duchenne muscular dystrophy via cell fusion and myogenic transdifferentiation,” Molecular Biology of the Cell, vol. 18, no. 5, pp. 1586–1594, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Angle, “Regenerative medicine with endometrial regenerative cells for critical ischemia: limb salvage from the cradle of life?” Future Cardiology, vol. 4, no. 6, pp. 547–550, 2008. View at Publisher · View at Google Scholar
  16. T. E. Ichim, D. T. Alexandrescu, F. Solano et al., “Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy,” Cellular Immunology, vol. 260, no. 2, pp. 75–82, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. W. Zou, J. D. Wolchok, and L. Chen, “PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: mechanisms, response biomarkers, and combinations,” Science Translational Medicine, vol. 8, no. 328, article 328rv4, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. S. L. Topalian, C. G. Drake, and D. M. Pardoll, “Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity,” Current Opinion in Immunology, vol. 24, no. 2, pp. 207–212, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Dong and X. Chen, “Immunoregulatory role of B7-H1 in chronicity of inflammatory responses,” Cellular & Molecular Immunology, vol. 3, no. 3, pp. 179–187, 2006. View at Google Scholar
  20. T. J. Curiel, S. Wei, H. Dong et al., “Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity,” Nature Medicine, vol. 9, no. 5, pp. 562–567, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. H. Dong, S. E. Strome, D. R. Salomao et al., “Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion,” Nature Medicine, vol. 8, no. 8, pp. 793–800, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. J. A. Brown, D. M. Dorfman, F. R. Ma et al., “Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production,” The Journal of Immunology, vol. 170, no. 3, pp. 1257–1266, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. I. Kryczek, S. Wei, W. Gong et al., “Cutting edge: IFN-γ enables APC to promote memory Th17 and abate Th1 cell development,” The Journal of Immunology, vol. 181, no. 9, pp. 5842–5846, 2008. View at Publisher · View at Google Scholar
  24. H. Sheng, Y. Wang, Y. Jin et al., “A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1,” Cell Research, vol. 18, no. 8, pp. 846–857, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. K. N. Sivanathan, S. Gronthos, D. Rojas-Canales, B. Thierry, and P. T. Coates, “Interferon-gamma modification of mesenchymal stem cells: implications of autologous and allogeneic mesenchymal stem cell therapy in allotransplantation,” Stem Cell Reviews, vol. 10, no. 3, pp. 351–375, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Banchereau and R. M. Steinman, “Dendritic cells and the control of immunity,” Nature, vol. 392, no. 6673, pp. 245–252, 1998. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Locati, A. Mantovani, and A. Sica, “Macrophage activation and polarization as an adaptive component of innate immunity,” Advances in Immunology, vol. 120, pp. 163–184, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. S. K. Biswas and A. Mantovani, “Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm,” Nature Immunology, vol. 11, no. 10, pp. 889–896, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. E. Pouliquen, A. Koenig, C. C. Chen et al., “Recent advances in renal transplantation: antibody-mediated rejection takes center stage,” F1000Prime Reports, vol. 7, p. 51, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. X. Zhang and E. F. Reed, “Effect of antibodies on endothelium,” American Journal of Transplantation, vol. 9, no. 11, pp. 2459–2465, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. M. C. Deng, T. D. T. Tjan, B. Asfour, N. Roeder, and H. H. Scheld, “Transplant vasculopathy,” Herz, vol. 23, no. 3, pp. 197–201, 1998. View at Publisher · View at Google Scholar · View at Scopus
  32. J. Wehner, C. N. Morrell, T. Reynolds, E. R. Rodriguez, and W. M. Baldwin, “Antibody and complement in transplant vasculopathy,” Circulation Research, vol. 100, no. 2, pp. 191–203, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. J. M. Aranda Jr and J. Hill, “Cardiac transplant vasculopathy,” Chest, vol. 118, no. 6, pp. 1792–1800, 2000. View at Publisher · View at Google Scholar · View at Scopus
  34. T. S. Lim, V. Chew, J. L. Sieow et al., “PD-1 expression on dendritic cells suppresses CD8+ T cell function and antitumor immunity,” Oncoimmunology, vol. 5, no. 3, article e1085146, 2016. View at Publisher · View at Google Scholar · View at Scopus
  35. H. C. Probst, K. McCoy, T. Okazaki, T. Honjo, and M. van den Broek, “Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4,” Nature Immunology, vol. 6, no. 3, pp. 280–286, 2005. View at Publisher · View at Google Scholar · View at Scopus
  36. B. Yuan, S. Huang, S. Gong et al., “Programmed death (PD)-1 attenuates macrophage activation and brain inflammation via regulation of fibrinogen-like protein 2 (Fgl-2) after intracerebral hemorrhage in mice,” Immunology Letters, vol. 179, pp. 114–121, 2016. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Roy, P. Gupta, S. Palit, M. Basu, A. Ukil, and P. K. Das, “The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani,” Clinical & Translational Immunology, vol. 6, no. 5, article e137, 2017. View at Publisher · View at Google Scholar
  38. A. Buermann, D. Römermann, W. Baars, J. Hundrieser, J. Klempnauer, and R. Schwinzer, “Inhibition of B-cell activation and antibody production by triggering inhibitory signals via the PD-1/PD-ligand pathway,” Xenotransplantation, vol. 23, no. 5, pp. 347–356, 2016. View at Publisher · View at Google Scholar · View at Scopus
  39. Y. Agata, A. Kawasaki, H. Nishimura et al., “Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes,” International Immunology, vol. 8, no. 5, pp. 765–772, 1996. View at Publisher · View at Google Scholar · View at Scopus
  40. Z. Zhong, A. N. Patel, T. E. Ichim et al., “Feasibility investigation of allogeneic endometrial regenerative cells,” Journal of Translational Medicine, vol. 7, no. 1, p. 15, 2009. View at Publisher · View at Google Scholar · View at Scopus
  41. T. E. Ichim, F. Solano, F. Lara et al., “Combination stem cell therapy for heart failure,” Internal Archives of Medicine, vol. 3, no. 1, p. 5, 2010. View at Publisher · View at Google Scholar · View at Scopus