Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice

Figure 3

Ephrin-B2-stimulated diabetic PB-MNC promote cell proliferation poststroke. (a) In the peri-infarct area at D3, Ki67+ cell numbers were significantly greater in the PB-MNC+ group versus the PBS group, but there were no significant differences between the PB-MNC group and the other two groups (/group). (b) In the subventricular zone at D3, there was a significant increase in Ki67+ cells in PB-MNC+-treated mice compared to PBS-treated mice (/group). By D14, no significant differences were evidenced between PB-MNC+, PB-MNC, and PBS (/group). There were no significant differences between D3 and D14 in the PBS and PB-MNC groups, whereas there were significantly fewer Ki67+ cells in the PB-MNC+ group. Data are presented as mean ± SD. ; . Scale bar = 200 μm.

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