Ephrin-B2-stimulated diabetic PB-MNC mice significantly increase angiogenesis in the peri-infarct area. Although microvessel density on D3 was not significantly different between the PB-MNC+, PB-MNC, and PBS groups (/group), it was significantly greater on D14 in the PB-MNC+ group than the PBS group. Between D3 and D14, microvessel density increased significantly in the PB-MNC+ group, but it did not change significantly in the PB-MNC or PBS groups. Data are presented as mean ± SD. . Scale bar = 400 μm.