The Mechanobiology of the Actin Cytoskeleton in Stem Cells during Differentiation and Interaction with Biomaterials

Figure 2

Molecular structure of contact adhesion. Different proteins are involved and are necessary for focal adhesion, like focal adhesion kinase (FAK), talin, vinculin, and paxilin, linking receptors with the cytoskeleton. Outside the membrane, adhesion receptors, like integrins and selectines link the membrane with the substrate (modified from P. Kanchanawong, copyright, 2010).