The Mechanobiology of the Actin Cytoskeleton in Stem Cells during Differentiation and Interaction with Biomaterials

Figure 3

Actin networks of MSCs visualized by a confocal microscope. hMSCs transfected with β-actin-RFP (red) and stained with DAPI (blue) (by Dr. Ambriz, 2016). Actin networks resemble the same pattern from Ingber’s model [47] in which tensed elastic strings and straws that are interconnected can predict the actomyosin complex behaviour. Actin filament orientation changes depending on its distance to the nucleus.