Human Endometrial Regenerative Cells Attenuate Bleomycin-Induced Pulmonary Fibrosis in Mice

Figure 1

ERCs ameliorate alveolitis and abrogate collagen deposition. (a) Representative figure of gross pathology. The lung in the sham control group presents as complete and smooth, while in the untreated group became inflamed and mauve and had fibrous deposition. After ERC treatment, it showed the reverse of the inflammation and partial fibrotic patches. (b) Wet/dry ratio evaluates the pulmonary edema which represents the severity of inflammation. ERCs reduced the level of wet/dry ratio in comparison with that of the untreated group. Bar graphs represent mean ± SEM of three separate experiments. values were determined by one-way ANOVA. Data shown are representative of three separate experiments performed. ( versus the sham control group. versus the untreated group, ). ERCs: endometrial regenerative cells.

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