Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Fas^lpr Mice

Figure 5

Combination effect of immunosuppressants and MSCs in vitro. T cells were loaded into a 96-well plate at 1 × 10⁵ cells/well. MSCs were loaded at 0.01, 0.03, or 0.1 × 10⁴ cells/well, or were omitted. Cells were treated with PD (a), PDL (b), MMF (c), or MPA (d). Concanavalin A was added at 1 μg/ml and T cell proliferation was measured 72 h later. versus control.

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(b)

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(d)