Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling

Figure 5

(a, b) Sitagliptin and sitagliptin + AMD3100 treatment had no significant influence on the total macrophage content in the injured and also in the uninjured carotid artery (n.s. = not significant). (c, d) The different treatments had no significant influence on the proportion of F4/80⁺Gr-1⁺ M1 and F4/80⁺CD206⁺ M2 macrophages (n.s. = not significant). (e) Representative dot plots from FACS analyses. Upper row shows F4/80⁺ total macrophages (right quadrant), and bottom row shows F4/80⁺Gr-1⁺ M1 (upper left quadrant) and F4/80⁺CD206⁺ M2 (bottom right quadrant) macrophages.

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