Review Article
Molecular Mechanisms of Transdifferentiation of Adipose-Derived Stem Cells into Neural Cells: Current Status and Perspectives
Table 4
Neural stem cell- or neural cell-specific microRNAs.
| miRNA | Effect on NSCs or neural cells | Target(s) | Ref. |
| miR-9 | Neural stem cell self-renewal | TLX (NR2E1), REST, FoxG1, Her5, Her9 | [94, 95] | miR-137 | Promotion of proliferation and repression of differentiation | Ezh2, PcG, MeCP2 | [96, 97] | let-7b | Inhibition of NSC proliferation and accelerated neural differentiation | Hmga2 | [98ā100] | miR-184 | Promotion of neural stem cell proliferation and inhibition of differentiation by targeting Numb-like | MBD1 | [101] | miR-124 | Neuronal differentiation | REST (NRSF), PTBP | [102] | miR-132 | Radial-glial stem cell self-renewal | CREB, Nurr1 | [103] | miR-138 | Synaptic plasticity | Lypla1 | [103] |
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