Review Article

Molecular Mechanisms of Transdifferentiation of Adipose-Derived Stem Cells into Neural Cells: Current Status and Perspectives

Table 4

Neural stem cell- or neural cell-specific microRNAs.

miRNAEffect on NSCs or neural cellsTarget(s)Ref.

miR-9Neural stem cell self-renewalTLX (NR2E1), REST, FoxG1, Her5, Her9[94, 95]
miR-137Promotion of proliferation and repression of differentiationEzh2, PcG, MeCP2[96, 97]
let-7bInhibition of NSC proliferation and accelerated neural differentiationHmga2[98ā€“100]
miR-184Promotion of neural stem cell proliferation and inhibition of differentiation by targeting Numb-likeMBD1[101]
miR-124Neuronal differentiationREST (NRSF), PTBP[102]
miR-132Radial-glial stem cell self-renewalCREB, Nurr1[103]
miR-138Synaptic plasticityLypla1[103]