Research Article
TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton
Table 2
Genes involved in osteogenesis-related pathways that are downregulated in CYD-treated hMSCs.
| Endochondral ossification | Actin cytoskeleton | Focal adhesion | TGFβ signaling | MAPK signaling |
| FGF2 | FGF1 | ITGA6 | UCHL5 | STMN1 | TGFB2 | FGF2 | STYK1 | CDC2 | DUSP1 | PLAT | FGF5 | CAV1 | SMURF2 | TRAF2 | CALM1 | FGF22 | CAV2 | NEDD9 | BDNF | ADAMTS1 | KRAS | CAV3 | STAMBPL1 | MAP3K5 | OPG | NRAS | LAMC2 | CCNB2 | ACVR1C | | C11orf13 | THBS1 | RBL1 | KRAS | | F2R | PXN | MAPK8 | TGFB2 | | CRK | RHOB | PARD6A | NRAS | | PAK1 | PDPK1 | CAV1 | PPP5C | | ARHGEF7 | MYLK2 | TFDP1 | PAK1 | | VIL2 | PAK1 | KLF6 | CRK | | PXN | MAPK8 | FST | MAPK8 | | | BCL2 | SERPINE1 | | | | CCND3 | THBS1 | | | | CRK | NOG | | | | | HRAS | |
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