Review Article

Intervertebral Disc-Derived Stem/Progenitor Cells as a Promising Cell Source for Intervertebral Disc Regeneration

Table 1

Surface markers of IVDSCs.

SpeciesCell typePositive markersNegative markersReferences

HumanNPSCCD73, CD90, and CD105CD34, CD45[47]
HumanNPSCCD73, CD90, and CD105CD34, CD45, and HLA-DR[43, 55]
RatNPSCCD44, CD90, and CD105CD34, CD45[50]
HumanNPSCCD29, CD44, and CD105CD14, CD34, CD45, and HLA-DR[34]
HumanNPSCTie2,GD2, Flt1, and CD271CD24[31]
Mini pigNPSCCD29, CD90, and CD44ā€”[42]
RatNPSCCD73, CD90, and CD105CD34, CD45[40]
HumanNPSCCD29, CD44, CD73, CD90, and CD105CD29, CD44, CD73, CD90, and CD105[23]
HumanNPSCCD90, CD73, CD105, CD106, and CD166CD14, CD19, CD24, CD34, CD45, and HLA-DR,[29]
HumanNPSCCD24, CD73, CD90, and CD105CD29, CD45[58]
Rhesus macaqueNPSCCD44, CD90, CD146, CD166, and HLA-DRCD90, CD271[39]
HumanAFSC, NPSCCD49a, CD63, CD73, CD90, CD105, CD166, p75 NTR, and CD133/1CD34[28]
Rhesus macaqueAFSCCD44, CD90, CD146, CD166, and HLA-DRCD29, CD106, and CD271[39]
HumanAFSCCD29, CD49e, CD51, CD73, CD90, CD105, CD166, CD184, nestin, and neuron-specific enolaseCD31, CD34, CD45, CD106, CD117, and CD133[35]
HumanAFSC, NPSC, and CESCCD73, CD90, and CD105CD19, CD34, CD45, and HLA-DR[38]
HumanCESCCD73, CD90, and CD105CD14, CD19, CD34, CD45, and HLA-DR[45, 59, 60]
HumanCESCCD73, CD90, CD105, and Stro-1CD14, CD19, CD34, CD45, and HLA-DR[36]
HumanCESCCD44, CD73, CD90, CD105, CD133, CD166, and Stro-1CD14. CD19, CD34, CD45, and HLA-DR[32]
RatSCNSCCD29, CD90, and CD44CD19, CD34, CD45, and CD11b[20]
HumanIVDSCCD90, CD105, and Stro-1ā€”[61]