Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats

Figure 6

The survival and migration of BMSCs 4 weeks after cell transplantation. (a–c) show the BMSC group, (d–i) show the H-BMSC group. (a), (d), and (g) show the cell nucleus image stained by DAPI. (b), (e), and (h) show GFP-positive cells. (c) Merges of (a) and (b) (100×). (f) Merges of (d) and (e) (100×). (i) Merges of (g) and (h) (400×). (j) shows the number of BMSC-GFP in the nucleus pulposus and annulus fibrosus regions. Data presented here is the mean ± SD. versus BMSC group ().

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)