Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats
Table 2
Effect of CoCl2 on the proliferation of BMSCs detected by CCK-8 assay.
Concentration/time
0 h
6 h
12 h
24 h
48 h
0 μM
1.01 ± 0.06
1.11 ± 0.09
1.41 ± 0.18#
1.82 ± 0.19
2.6 ± 0.18#
10 μM
1.00 ± 0.08
1.05 ± 0.09
1.30 ± 0.13#
1.56 ± 0.18
2.38 ± 0.10#
50 μM
1.00 ± 0.09
0.95 ± 0.12
1.14 ± 0.18
1.30 ± 0.12
1.75 ± 0.16
100 μM
1.01 ± 0.10
0.85 ± 0.14
0.98 ± 0.12#
1.15 ± 0.11
1.41 ± 0.11#
200 μM
1.03 ± 0.09
0.80 ± 0.17
0.88 ± 0.15
0.95 ± 0.16
0.89 ± 0.13
300 μM
1.01 ± 0.06
0.72 ± 0.10
0.58 ± 0.13
0.44 ± 0.28
0.24 ± 0.10
versus 100 μM group, versus 24 h group (mean ± SD, n = 6).
