Retention and Functional Effect of Adipose-Derived Stromal Cells Administered in Alginate Hydrogel in a Rat Model of Acute Myocardial Infarction

Figure 1

Experimental setup. Myocardial infarction was induced and rats were treated with either saline, ASCs in saline, or ASCs in alginate hydrogel on day 0. The ASCs were tracked at days 1, 3, 7, 14, and 21 after administration, with a subgroup being tracked 6 hours after injection. Functional measurements were obtained using cardiac magnetic resonance imaging (cardiac MRI) and rubidium-82 positron emission tomography/computer tomography (⁸²Rb-PET/CT) at days 1, 14, and 28 postoperation.