Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats

<div>Immunostaining for GST-P (A–D) and PCNA (E–H) in livers of rats in the normal group (A, E), PBS group (B, F), CSC-Ex group (C, G), and MSC-Ex group (D, H). Arrowhead points to PCNA-positive nucleus. Scale bar: (A) E–H, 50 <i>μ</i>m, B–D, 30 <i>μ</i>m. The graphs show mean number and area of GST-P-positive foci and number of PCNA-positive nuclei in different rat groups. 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Stem Cells International

fig6

Figure 6

Figure 6: Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats 