Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

Figure 6

Comparison of the time-variant state transition rate for MSCs cultured under hypoxia and normoxia in experiment A. The three parameters used to simulate the logistic function defined in (2) can be found in Table 1, of which the midpoint time is annotated in the figure as and for normoxia and hypoxia, respectively.