Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

Figure 8

Experimental measurements and model-predicted population dynamics of MSCs under hypoxia and normoxia in experiment B. For the series of growth curves under hypoxia, the first four parameters are fixed (see Table 2), while the last parameter varies from 90 to 120 equidistantly to demonstrate its significant effect on cell proliferation. PD: cumulative population doublings.