Protein Kinases and Their Inhibitors in Pluripotent Stem Cell Fate Regulation

Figure 2

Pharmacological regulation of pluripotent stem cell fate by selective protein kinase inhibitors. Small molecule compounds modulating the activities of protein kinases facilitate the somatic reprogramming process toward the pluripotent state, promote the conversion of different pluripotent states, regulate self-renewal growth, and promote differentiation/lineage specification of PSCs.