Review Article
Minimally Manipulated Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review of Clinical Evidence
Table 4
SVF study quality assessment with the Coleman methodology score modified by Kon et al.
| | Study | TOT | Study size | Mean f-up | Different surg proc | Type of study | Surg proc description | Postop rehab | MRI outcome | Histological outcome | Outcome criteria | Assessment of clinical outcome | Selection process |
| | Adipose-derived stem cells | Jones et al. [28] | 54 | 7 | 0 | 10 | 15 | 5 | 0 | 0 | 0 | 5 | 9 | 3 | | Roato et al. [29] | 67 | 0 | 2 | 10 | 10 | 5 | 5 | 10 | 10 | 5 | 7 | 3 | | Hong et al. [33] | 56 | 4 | 2 | 4 | 15 | 5 | 5 | 10 | 0 | 5 | 3 | 3 | | Hudetz et al. [26] | 53 | 4 | 2 | 10 | 10 | 5 | 0 | 10 | 0 | 5 | 7 | 0 | | Bansal et al. [30] | 45 | 0 | 5 | 4 | 10 | 5 | 0 | 10 | 0 | 5 | 3 | 3 | | Yokota et al. [27] | 34 | 0 | 0 | 10 | 10 | 5 | 2 | 0 | 0 | 2 | 5 | 0 | | Nguyen et al. [37] | 51 | 4 | 2 | 4 | 10 | 5 | 5 | 10 | 0 | 5 | 3 | 3 | | Koh et al. [36] | 36 | 4 | 5 | 4 | 10 | 5 | 0 | 0 | 0 | 5 | 3 | 0 | | Kim et al. [34] | 47 | 7 | 5 | 4 | 10 | 5 | 5 | 0 | 0 | 5 | 3 | 3 | | Koh et al. [32] | 45 | 7 | 5 | 4 | 10 | 5 | 0 | 0 | 0 | 5 | 3 | 6 | | Koh et al. [35] | 40 | 10 | 5 | 4 | 0 | 5 | 5 | 0 | 0 | 5 | 3 | 3 | | Pham 2014 Biomed Res | 44 | 4 | 0 | 4 | 10 | 5 | 0 | 10 | 0 | 5 | 3 | 3 | | Koh et al. [38] | 40 | 4 | 5 | 4 | 0 | 5 | 2 | 10 | 0 | 5 | 2 | 3 |
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