Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment

Table 5

Modified Coleman methodology score for studies using BMAC for knee cartilage repair.

Section score (maximum score)	Mean	Standard deviation	Range	Median	25th to 75th percentile
Part A
Study size (10)	2.81	3.37	0-10	0	(0-5.5)
Mean duration of follow-up (10)	3.40	2.8	0-10	2	(2-5)
No. of surgical procedures (10)	9	2	4-10	10	(10-10)
Type of study (15)	4.2	5.8	0-15	0	(0-10)
Description of surgical procedure (5)	4.5	0.87	3-5	5	(4-5)
Description of postoperative rehabilitation (5)	2.45	2.41	0-5	2	(0-5)
Inclusion of MRI (10)	6.36	4.57	0-10	10	(0-10)
Inclusion of histological outcome (10)	3.3	3.88	0-10	0	(0-5)
Part B
Outcome measures (5)	3.9	1.47	0-5	5	(3-5)
Outcome assessment (9)	5.56	2.09	2-9	5	(5-7)
Selection process (11)	9.3	2.6	3-11	11	(8-11)
Total part A (75)	36.2	10.03	14-54	37	(28-44)
Total part B (25)	18.7	4.99	5-25	19	(16-22)
Total score (100)	55	12.36	32-77	57	(45.5-63.5)