NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

<div>Phalloidin staining (green) of BMSCs after treatment with the NOTCH inhibitor GSI XII. Cells were incubated with 2 <i>μ</i>M (b) and 4 <i>μ</i>M (c) GSI XII for 24 h; DMSO-treated cells served as a control (a). Representative images of one donor of three independent experiments are shown. DAPI (blue) was used for nuclear staining. The bar represents 50 <i>μ</i>m.</div>

Stem Cells International

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Figure 5

Figure 5: NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells 