Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone Marrow MSCs

<div>Histological staining of human periosteum samples, harvested close to a fracture site. (a) H&amp;E staining of periosteum sample showing the cellular inner cambium layer (<i>C</i>), the lining cortical bone (<i>CB</i>), and the outer fibrous layer (<i>F</i>). (b) Picro sirius red, imaged using polarised light, showed collagen as the dominant feature of periosteum. CD271 candidate MSC marker immunohistochemistry staining was carried out on (c) periosteum, where staining was shown in the cambium layer and surrounding blood vessels throughout the fibrous layer and (d) iliac crest bone samples, where staining was within the bone marrow and lining the bone.</div>

Stem Cells International

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Figure 1: Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone Marrow MSCs 

Figure 1 | Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone Marrow MSCs 