Stem Cells International / 2019 / Article / Fig 4

Research Article

Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells

Figure 4

M1 does not alter ATP synthase subunit expression or interact with any of the 468 human protein kinases screened. (a) mRNA () and (b) protein () expression of ATP synthase subunits in human iPSCs (iPSC-Foreskin-2 cell line) cultured in TeSR-E8 and treated with M1 for 48 hours. (c) Kinase interaction map of M1 at 10 μM with 468 human protein kinases. Zero interactions with a binding score of ≥35% relative to DMSO were identified. Data are expressed as and analyzed by one-way paired ANOVA with Dunnett’s post hoc test.
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