Influence of Lineage-Negative Stem Cell Therapy on Articulatory Functions in ALS Patients

Table 4

The CSF concentrations of TNF-α, BDNF, NGF-β, CRP, NT-3, and TNF-R in groups I, II, and III (0 and 7^th days).

Concentration in CSF	Group I ()			Group II ()			Group III ()
	Median (pg/ml)	Interquartile range	value	Median (pg/ml)	Interquartile range	value	Median (pg/ml)	Interquartile range	value
TNF-α 0 d	2.88	0.29	0.068	3.31	0.58	0.409	3.026	0.58	0.180
TNF-α 7 d	3.31	0.29		3.17	0.29		3.32	0.00
BDNF 0 d	2.45	0.45	0.144	3.75	2.17	0.262	3.27	1.71	0.990
BDNF 7 d	3.35	0.30		3.64	1.48		3.27	1.63
NGF-β 0 d	0.74	0.20	0.500	0.84	0.20	0.948	0.95	0.16	0.109
NGF-β 7 d	0.84	0.20		0.84	0.20		0.74	0.00
CRP 0 d	31104	30462	0.043	11667	24463	0.807	6472	40628	0.593
CRP 7 d	6680	16966		5144	34944		9862	36053
NT-3 0 d	352.73	0.00	1.000	352.73	113.79	0.675	352.73	168.26	0.180
NT-3 7 d	352.73	54.47		352.73	107.39		352.73	233.68
TNF-R 0 d	918.28	144.34	0.138	1006.18	190.83	0.115	1086.91	277.03	0.285
TNF-R 7 d	1176.05	335.68		1073.01	364.67		1070.30	318.57

Data are expressed as median (interquartile range); value—0 day vs. 7^th day; for difference between group I and II patients; Mann-Whitney test.