Wharton’s Jelly Mesenchymal Stem Cell Administration Improves Quality of Life and Self-Sufficiency in Children with Cerebral Palsy: Results from a Retrospective Study
Table 1
Clinical (SI) and parental qualitative assessment of improvement in different areas.
Area
Clinical assessment
Parental assessment
Improvement: (%)
value
(%)
value
Muscle tension
26 (48.1)
0.000001
12 (52.2)
0.0015
Muscle strength
8 (14.8)
0.007
4 (17.4)
NS
Gross motor development
9 (16.7)
0.004
11 (47.8)
0.0026
Fine motor development
4 (7.4)
NS (0.07)
5 (21.7)
NS (0.07)
Nutritional functions
4 (7.4)
NS (0.07)
3 (13.0)
NS
Senses
4 (7.4)
NS
3 (13.0)
NS
Micturition/defecation control
2 (3.7)
NS
1 (4.3)
NS
Sleeping
1 (1.9)
NS
4 (17.4)
NS
Circulation
2 (3.7)
NS
1 (4.3)
NS
Epilepsy attacks
4 (12.9)
NS
3 (9.7)
NS
Drug dosage
1 (1.9)
NS
4 (17.4)
NS
Emotions
1 (1.9)
NS
9 (39.1)
0.008
Communication
12 (22.2)
0.0009
13 (56.5)
0.0009
Attention
10 (18.5)
0.004
10 (43.5)
0.004
Cognitive functions
33 (61.1)
<0.000001
10 (43.5)
0.004
Engagement (motivation/initiative/cooperation)
3 (5.6)
NS
12 (52.2)
0.0015
Social interactions
5 (9.2)
0.04
12 (52.2)
0.0015
Number of areas
17
9 significant +2 with tendency
17
8 significant +1 with tendency
Subgroup with epilepsy; value is given for sign test. NS: not significant; deteriorations are reported as adverse events.
