| | Integrin heterodimers | Ligands | Pathway | Ref. |
| | Collagen receptor | α1β1 | Collagen (IV, I, and IX) | (i) RhoA/ROCK | [51] | | α2β1 | Collagen (I, IV, and IX) | (i) RhoA/ROCK
(ii) YAP/TAZ | [52] | | α10β1 | Collagen (IV, VI, II, and IX) | (i) RhoA/ROCK | [51] | | α11β1 | Collagen (I, IV, and IX) | (i) RhoA/ROCK |
| | Laminin receptor | α3β1 | Laminin (LN-511, LN-332, and LN-211) | (i) RhoA/ROCK | [51] | | α7β1 | Laminin (LN-511, LN-211, LN-411, and LN-111) | (i) RhoA/ROCK | | α6β1 | Laminin (LN-511, LN-332, LN-111, and LN-411) | (i) RhoA/ROCK | | α6β4 | Laminin (LN-332, LN-511) | / | |
| | RGD receptor | ανβ1 | Fibronectin, vitronectin (RGD) | (i) RhoA/mDia | | | ανβ3 | Vitronectin, fibronectin, and fibrinogen (RGD) | (i) RhoA/mDia
(ii) MKL-1/SRF
(Responsible for the increase in the number of FA and cell spreading areas) | [17, 18, 50, 53] | | ανβ5 | Vitronectin (RGD) | (i) RhoA/mDia
(Responsible for the increase in the number of FA and cell spreading areas) | [17, 53] | | ανβ6 | Fibronectin, TGF-β-LAP (RGD) | / | | | ανβ8 | Vitronectin, TGF-β-LAP (RGD) | / | | | α5β1 | Fibronectin (RGD) | In the leading edge of moving cells in the 2D surface | [16] | | α8β1 | Fibronectin, vitronectin, and nephronectin (RGD) | / | | | αIIbβ3 | Fibrinogen, fibronectin (RGD) | / | |
| | Leucocyte-specific receptor | α9β1 | Tenascin-C, VEGF-C, and VEGF-D | / | | | α4β1 | Fibronectin, VCAM-1 (LDV) | / | | | α4β7 | MadCAM-1 (LDV), fibronectin, and VCAM-1 | / | | | αDβ2 | ICAM-3, VCAM-1 | / | | | αEβ2 | E-cadherin | / | | | αLβ2 | ICAM-1, ICAM-2, ICAM-3, and ICAM-5 | / | | | αMβ2 | iC3b, fibrinogen | / | | | αXβ2 | iC3b, fibrinogen | / | |
|
|
