|
| Authors/country | Diagnosis | No. of treated patients | Stem cell type | Transplant type | Dose per injection | Injection frequency | Follow-up | Adverse events (person-time) |
|
| Bonab et al. [23]/Iran | MS | 10 | Auto-BM-MSCs | IT | | 1 | 13–26 months | Slight headache (9); iatrogenic meningitis (2) |
| Pal et al. [27]/India | SCI | 30 | Auto-BM-MSCs | IT | | 2–3, weekly | 12–24 months | None |
| Karussis et al. [16]/Israel | MS
ALS | 15
19 | Auto-BM-MSCs | IT+IV |
| 1 | 25 months | Fever (21); headache (15); meningism (1); rigidity (2); leg pain (3); dyspnoea (1); confusion (1); neck pain (1); difficulty walking/standing (4) |
| Yamout et al. [24]/Lebanon | MS | 7 | Auto-BM-MSCs | IT | | 1 | 12 months | Seizures (1); cervical and lower back pain (3) |
| Kishk et al. [28]/Egypt | SCI | 44 | Auto-BM-MSCs | IT | | 6, monthly | 12 months | Encephalomyelitis (1); neuropathic pain (24); sweating (3); transient hypertension (3); spasticity (4); dyspnoea (1); jerky movements (2) |
| Hammadi et al. [25]/Iraq | MS | 50 | Auto-PB MSCs | IT | | 1–8 (mean 2.14) | 12 months | Backache (45); meningism (45) |
| Bonab et al. [26]/Iran | MS | 25 | Auto-BM-MSCs | IT | | 1 | 12 months | Fever (25); nausea/vomiting (2); headache (3); lower limb weakness (2) |
| Karamouzian et al. [29]/Iran | SCI | 11 | Auto-BM-MSCs | IT | | 1 | 12–33 months | Pain (8) |
| Tian et al. [33]/China | TBI | 97 | Auto-BM-MSCs | IT | | 1 | 2 weeks | Fever (5); headache (2) |
| Kim et al. [17]/Korea | ALS | 37 | Auto-BM-MSCs | IT | | 2, monthly | 6 months | Fever (11); myalgia (9); lower back pain (4); headache (4) |
| Oh et al. [18]/Korea | ALS | 8 | Auto-BM-MSCs | IT | | 2, at 26-day intervals | 12 months | Fever (4); administration site pain (3); headache (3) |
| Rushkevich et al. [19]/Belarus | ALS | 10 | Auto-BM-MSCs | IT+IV | | 1–2, at 5–7-month intervals | 12 months | Fever (1); headache (2) |
| Petrou et al. [20]/Israel | ALS | 26 | Auto-BM-MSCs | IT+IV | | 1 | 6 months | Headache (13); fever (11); back/leg pains (8); vomiting (3); neck stiffness (2); general weakness (1); bruising (1); spasticity (1) |
| Satti et al. [31]/Pakistan | SCI | 9 | Auto-BM-MSCs | IT | | 2–3, monthly | 269–826 days | Headache (1); tingling sensation (2) |
| Hlebokazov et al. [34]/Belarus | EP | 10 | Auto-BM-MSCs | IT+IV | | 1 | 12 months | Headache (1) |
| Hur et al. [30]/Korea | SCI | 14 | Auto-AD MSCs | IT | | 3, monthly | 8 months | Urinary tract infection (1); headache (2); nausea and vomiting (1) |
| Staff et al. [21]/USA | ALS | 27 | Auto-AD MSCs | IT | | 1–2, monthly | 4–108 weeks | Headache (3); back/leg pain (9) |
| Liu et al. [35]/China | CP | 33 | Auto-BM-MSCs | IT | | 4, at 3–4-day intervals | 12 months | Fever (2); nausea, vomiting, and headache (4) |
| Sykova et al. [22]/Czech | ALS | 26 | Auto-BM-MSCs | IT | | 1 | 18 months | Headache (7); hyperhidrosis (1); leukocytosis (2) |
| Vaquero et al. [32]/Spain | SCI | 10 | Auto-BM-MSCs | IT | | 4, 3 months | 12 months | Hypertension (1); local pain (1); leg pain (1); urinary tract infection (3); headache (4); hyperthermia (1); wound (1); infected pressure ulcer (1); arthralgia (1); syncope (1); pain in coccyx (1); neck pain (1); back pain (1); nasopharingytis (1); bronchitis (1) |
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