Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats

Figure 1

Schematic of the basic process of the present study. NPMSC were isolated from the coccygeal IVD of SD rats, and amplification was performed in vitro. After IDD model induction by a 21G needle, injectable hydrogel-loaded NPMSC was transplanted into the degenerated NP by a microsyringe.