Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties
Relationship between NRS and size for HSC populations before and after separation using Device C. (a) Correlative relationship between NRS and HSC diameter before separation. NRS is weakly and negatively correlated with diameter. . (b) Correlative relationship between NRS of HSCs collected from inner and outer outlets. Four distribution patterns were identified with cells harvested from the outer outlet located mostly at the right (O1) and top (O2) of the distribution graph and cells harvested from the inner outlet located mostly at the left (I1) and bottom (I2). The numbers 1 and 2 simply denote whether the cells are on the far ends of the diameter range (I1 and O1) or in the midrange (I2 and O2). .
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