Research Article

Wnt-GSK3β/β-Catenin Regulates the Differentiation of Dental Pulp Stem Cells into Bladder Smooth Muscle Cells

Figure 6

Wnt/GSK3β/β-catenin is involved in the process of SMC differentiation from the DPSC clone A32 through regulation of growth factors.The A32 clone was induced following the SMC induction protocol with or without the Wnt/β-catenin-specific inhibitor, XAV939, as well as the GSK3 inhibitors, SB216763 and LiCl, for 14 d. The mRNA expression of TGF-β1 (a), HGF (b), PDGF-BB (c), and VEGF (d) were analysed with qPCR. Statistical analysis was performed by using one-way ANOVA. Data are shown as . when compared with the control group.
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