Research Article

Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome

Figure 7

Summary of IPA analysis. The main upregulated canonical pathways are shown. Riboflavin metabolism and LXR/RXR and FXR/RXR activation remain statistically significant even after correction for multiple comparisons (Threshold indicates false discovery rate corrected p-value of 0.05). Bottom axis depicts the ratio of the number of genes upregulated in de CACiv signature divided by the total number of genes involved in a given pathway (squares).