Stem Cells International / 2019 / Article / Fig 2

Review Article

The Application of Induced Pluripotent Stem Cells in Pathogenesis Study and Gene Therapy for Vascular Disorders: Current Progress and Future Challenges

Figure 2

Overview of general strategies for human induced pluripotent stem cell-derived vascular cell generation. Somatic cells can be reprogrammed into human induced pluripotent stem cells (hiPSCs) by transduction of Yamanaka factors or chemical/small molecules, and the hiPSC can be further induced into several functional vascular cell types for vascular injury repair by different methods.