Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System

<div>Spontaneous differentiation of iPSCs after expansion in QES. (a) Floating embryoid bodies (EB) 7 days after aggregation. (b) Colony morphology after attachment. (c) Expression of markers of three embryonic germ layers by RT-PCR when cultivated on Matrigel (CTRL1) or after QES expansion on LN521 and VN. Scale bars represent 100 <i>μ</i>m.</div>

Stem Cells International

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Figure 4: Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System 