Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord

<div>The immunocytochemical analysis of osteopontin (green) expression in WJ-MSC cultured on the Bio-Oss® Collagen scaffold after osteodifferentiation. (a) Confocal imaging shows osteopontin expression in single cells; specific staining was localized to the cytoplasm. (b) 3D cross-sectional image illustrates the distribution of WJ-MSC expressing osteopontin inside the skeleton. The nuclei were stained with Hoechst (blue). Scale bar: 50 <i>μ</i>m.</div>

Stem Cells International

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Figure 7

Figure 7: Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord 