Research Article
Multimodal Therapeutic Effects of Neural Precursor Cells Derived from Human-Induced Pluripotent Stem Cells through Episomal Plasmid-Based Reprogramming in a Rodent Model of Ischemic Stroke
Figure 6
Poststroke inflammation analyses in MCAo rats with ep-iPSC-NPC transplantation. (a) Double immunofluorescence staining of ED1/CD206 in the brains of rats of the ep-iPSC-NPC, fibroblast, and vehicle groups ( in each group). (b) Double immunofluorescence staining of ED1/iNOS in the brains of rats of the ep-iPSC-NPC, fibroblast, and vehicle groups ( in each group). All samples were counterstained with DAPI (blue). Scale bars: 50 μm. Data were shown as (SEM), by one-way ANOVA. ep-iPSC-NPCs: neural precursor cells differentiated from induced pluripotent stem cells; iNOS: inducible nitric oxide synthase; MCAo: middle cerebral artery occlusion.
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