Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation

Figure 5

ACTA2 downregulation increased active RhoA and downregulated Rac1 expression. (a) Bands represented the expression of RhoA, Rac1, and CDC42. Total RhoA and GAPDH was used as a loading control. (b) Quantification of active RhoA expression from (a) ( for each group). , one-way ANOVA followed by Tukey’s post hoc test. (c) Quantification of Rac1 expression from (a) ( for each group). , one-way ANOVA followed by Tukey’s post hoc test. (d) Quantification of CDC42 expression from (a) ( for each group).

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