Stem Cells International / 2020 / Article / Fig 3

Research Article

5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells

Figure 3

5-AzaC induces cardiomyocyte-like morphology in BM-VSELs. (a) 5-AzaC-induced VSELs showed morphological changes at day 7, and the population of cardiomyocytes peaked at day 14. (b) Growth of VSELs treated with different concentrations of 5-AzaC (1 μM, 10 μM, and 30 μM). (c) MTT assay indicated VSEL growth induced by different concentrations of 5-AzaC over time. (d) Morphological changes in BM-VSELs after treatment with 10 μM 5-AzaC. The arrow indicates that VSELs developed embryoid body-like structures after 5-AzaC treatment.

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