Amygdalin Promotes Fracture Healing through TGF-β/Smad Signaling in Mesenchymal Stem Cells

Figure 6

Amygdalin promoted bone fracture healing in the Cre-negative group compared with the Tgfβr2^Gli1Cre group. (a) Phospho-Smad2 protein expression was assessed by immunohistochemistry in the Cre-negative and Tgfβr2^Gli1Cre groups (day 7). . (b) X-ray results of fractures in the amygdalin-treated Tgfβr2^Gli1Cre group and Cre-negative mice. Red arrows indicate fracture lines. (c, d) μCT analysis of the bone volume and BV/TV (%) in callus tissues at days 7, 10, 14, and 21 postfracture in amygdalin-treated Tgfβr2^Gli1Cre and Cre-negative mice. . Data are presented as (SD). , .

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