Mechanisms of Cytotoxicity of Chemical Agents to Giant Cell Tumors: An In Vitro Study

Figure 2

Morphological appearance of the cultured GCT cells. (a) Cell morphology of the explant method on day 7 (magnification 100x). (b) Cell morphology of the collagenase method on day 8 (magnification 100x). The cells of both methods were able to grow, producing the elongated, spindle-shaped, and round-epithelioid cells. (c) The cells of the explant method at week two (magnification 200x). (d) The cells of the collagenase method at week two (magnification 200x). The multinucleated giant cells along with the spindle-shaped and round-epithelioid cells appeared.

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