The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">SUMO family members</td><td class="align_center"><i>Homo sapiens</i></td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">SUMO</td><td class="align_center">SUMO-1, -2, -3, -4</td></tr><tr><td class="align_left">SUMO-activating enzyme E1</td><td class="align_center">SAE1, SAE2</td></tr><tr><td class="align_left">SUMO-conjugating enzyme E2</td><td class="align_center">Ubc9</td></tr><tr><td class="align_left">SUMO-ligase E3</td><td class="align_center">Ranbp2; protein inhibitor of activated STAT (PIAS)1, -2, -3, -4; Nse2Mms21; etc.</td></tr><tr><td class="align_left">SUMOylation proteases</td><td class="align_center">SENPs, DeSI1, DeSI2, USPL1, etc.</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Stem Cells International

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Table 1

Table 1: The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review 