Bmi1 Severs as a Potential Tumor-Initiating Cell Marker and Therapeutic Target in Esophageal Squamous Cell Carcinoma
High expression of Bmi1 in esophageal carcinoma. (a) The TCGA database demonstrated that Bmi1 gene expression was significantly upregulated in esophageal carcinoma tissues. (b) Bmi1 expression levels in ESCA based on tumor histology were compared with normal tissues in the TCGA database (). (c) Bmi1 expression levels in different grades of esophageal carcinoma from TCGA database. (d) Gastroesophageal reflux is more likely to occur in patients with high expression of Bmi1. No = patients without gastroesophageal reflux; Yes = patients with gastroesophageal reflux; NA = data missing. .
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