Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration

Figure 1

Micro-CT and H&E staining analysis of bone defects treated with DIM at 4, 8, and 12 weeks after surgery. (a) Image of a rat critical-sized calvarial defect model and DIM implantation. (b) Relative 3D reconstruction parameter BV/TV of newly formed bone by micro-CT. , , and . (c) Relative 3D reconstruction parameter BMD of newly formed bone by micro-CT. and . (d) 3D reconstruction of calvarial defects and exemplary axial sections by micro-CT. (e) Representative coronal images of calvarial defects by H&E staining. .

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