Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases

Figure 1

Kidney development stages and expression of transcription factors. OSR1 and WT1 are expressed in the intermediate mesoderm; SIX2, PAX2, WT1, HOX11, and GDNF are expressed in the metanephric mesenchyme; coexpression of SIX2, SALL1, WT1, and PAX2 characterizes a NPC.